Clinical Trials Genotyping

At DNAVision, we genotype volunteers and patients participating in clinical trials. Why ?

The FDA, EMEA and other regulatory agencies are now requiring more information about clinical trial data on defined populations of subjects for new investigational drugs, so pharmaceutical companies, clinical research organizations and site management organizations have an immediate need for genotyping services.

Measuring the genetic variation of a clinical trial population can improve the design and increase the value of the trial by:

Understanding the results of the trial in terms of the individual differences of the trial population
Pre-selecting patients most likely to benefit from the proposed therapy
Reducing the size of the trial by using a defined population with an improved chance of a good response

Reduce risk by making an early assessment of the impact of inter-individual and population differences in drug metabolism.

DME Genotyping services

Increase confidence by adjusting dose for metabolism and correlating efficacy with genotype.

DME Genotyping services
Low throughput custom SNP genotyping services
High throughput custom SNP genotyping services

Predict efficacy and safety through the application of pharmacogenetic testing.

DME Genotyping services
Low throughput custom SNP genotyping services
High throughput custom SNP genotyping services

Samples

Clients submit purified genomic DNA or EDTA-preserved blood.

Results

Final Reports include SNP profiles for each patient sample.

Workflow