CYP2D6 Genotyping

Our CYP2D6 Molecular Assays consist in the detection of the principal variants responsible for abnormal metabolism status. These assays are ISO17025 accredited by BELAC and CLIA registered.

List of variants analysed:

Variant	Alleles	Activity
Wild type Duplication of *1 Deletion -1584C>G 100C>T 124G>A 883G>C 1023C>T 1707T>del 1758G>T 1846G>A 2549A>del 2613-2615 del AGA 2850C>T 2935A>C	1 Dupl. 5 2A Promoter 4,10 12 11 17 6 8 4 3 9 2, 17 7	Normal Ultra Null Decr. Decr. Null Null Decr. Null Decr. Null Null Decr. Decr. Null

We provide also Roche Amplichip CYP450 (IVD) for CYP2D6 & CYP2C19.

Laboratory Process

Specimen Requirements

These drugs have an information regarding importance of genetic variability contained in product labeling. We provide pharmacogenetic assays for the following drugs:

Peripheral Blood
- 5 ml in potassium EDTA (purple/lavender-top) tube
- Refrigerate specimen. Use cold pack for transport. Be sure cold pack is not in direct contact with specimen during transport.
- Sample must be submitted in less than 5 days from patient draw date.
Buccal swabs
FTA cards

Turnaround Time

1 week

Report

A report will be generated including mutations that have been detected and in the case of mutants, the inferred metabolism status.

Prices and Ordering

Please inquire for prices and ordering information.